Kai Chen Selected Research

Integrin alphaVbeta3

3/2009	RGD-human serum albumin conjugates as efficient tumor targeting probes.
11/2008	Integrin alphavbeta3-targeted radioimmunotherapy of glioblastoma multiforme.
8/2008	PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles.
6/2008	(68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression.
3/2008	18F-labeled BBN-RGD heterodimer for prostate cancer imaging.
11/2007	Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature.
11/2007	Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression.
11/2007	PET imaging of acute and chronic inflammation in living mice.
9/2007	microPET of tumor integrin alphavbeta3 expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4).
7/2007	(64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression.

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Kai Chen Research Topics

Disease

219	Neoplasms (Cancer) 11/2022 - 02/2002
54	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2006
34	Neoplasm Metastasis (Metastasis) 07/2021 - 08/2006
33	Inflammation (Inflammations) 07/2022 - 02/2005
25	Infections 01/2022 - 01/2013
23	Pancreatic Neoplasms (Pancreatic Cancer) 03/2022 - 02/2002
19	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 07/2002
19	Hypertension (High Blood Pressure) 01/2022 - 08/2002
14	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 11/2014
13	Bone Resorption 01/2022 - 11/2016
12	Cardiovascular Diseases (Cardiovascular Disease) 05/2022 - 07/2005
12	Neuroblastoma 01/2022 - 11/2016
12	Osteoporosis 10/2021 - 01/2002
11	Heart Failure 01/2022 - 06/2011
11	Colorectal Neoplasms (Colorectal Cancer) 09/2021 - 10/2004
10	Lung Neoplasms (Lung Cancer) 11/2022 - 10/2004
10	Glioblastoma (Glioblastoma Multiforme) 06/2022 - 12/2006
10	Adenocarcinoma 06/2022 - 07/2016
10	Alzheimer Disease (Alzheimer's Disease) 04/2022 - 02/2009
10	Wounds and Injuries (Trauma) 03/2022 - 02/2009
10	Prostatic Neoplasms (Prostate Cancer) 04/2020 - 10/2004
9	Atherosclerosis 03/2022 - 07/2003
9	Carcinogenesis 03/2022 - 06/2012
9	Leukemia 06/2021 - 01/2015
9	Osteosarcoma (Osteogenic Sarcoma) 01/2021 - 08/2010
9	Stomach Neoplasms (Stomach Cancer) 01/2021 - 10/2005
9	Carcinoma (Carcinomatosis) 10/2020 - 06/2008
8	Triple Negative Breast Neoplasms 01/2022 - 11/2016
8	Myocardial Infarction 01/2022 - 07/2005
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 01/2015
7	Hypoxia (Hypoxemia) 07/2022 - 06/2010
7	Ischemia 01/2022 - 07/2005
7	Stroke (Strokes) 01/2022 - 01/2009
7	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2021 - 12/2017
7	Toxoplasmosis 08/2019 - 01/2017
6	Thrombosis (Thrombus) 11/2022 - 09/2003
6	Dehydration (Water Stress) 06/2022 - 08/2015
6	Lymphatic Metastasis 01/2022 - 01/2013
6	Diabetes Mellitus 01/2022 - 08/2005
6	Nasopharyngeal Carcinoma 01/2022 - 06/2008
6	Pain (Aches) 01/2022 - 03/2018
6	Vascular Diseases (Vascular Disease) 01/2022 - 02/2002
6	Body Weight (Weight, Body) 01/2021 - 06/2003
5	Sepsis (Septicemia) 07/2022 - 03/2011
5	COVID-19 07/2022 - 12/2020
5	Cholangiocarcinoma 06/2022 - 02/2002
5	Cardiogenic Shock 01/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

53	Proteins (Proteins, Gene)FDA Link 07/2022 - 09/2004
39	Pharmaceutical PreparationsIBA 01/2022 - 12/2006
29	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2011
27	Peptides (Polypeptides)IBA 11/2021 - 04/2006
23	IntegrinsIBA 12/2019 - 04/2006
20	Biological ProductsIBA 03/2022 - 12/2006
18	Messenger RNA (mRNA)IBA 07/2022 - 10/2004
15	Long Noncoding RNAIBA 09/2021 - 12/2017
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 12/2006
13	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 05/2013
12	MicroRNAs (MicroRNA)IBA 05/2022 - 01/2015
12	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 02/2002
12	Integrin alphaVbeta3IBA 03/2009 - 10/2006
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2022 - 07/2002
9	RNA (Ribonucleic Acid)IBA 12/2021 - 01/2016
9	AcidsIBA 01/2021 - 12/2006
9	EnzymesIBA 01/2021 - 03/2002
9	CytokinesIBA 01/2020 - 02/2005
9	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 01/2009 - 12/2006
8	VaccinesIBA 01/2022 - 01/2017
8	Transcription Factors (Transcription Factor)IBA 10/2021 - 05/2012
8	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2005
8	salicylhydroxamic acid (SHAM)IBA 01/2021 - 07/2005
8	Estrogen ReceptorsIBA 01/2020 - 02/2015
8	arginyl-glycyl-aspartic acidIBA 12/2012 - 04/2006
7	Interleukin-6 (Interleukin 6)IBA 01/2022 - 03/2011
7	LigandsIBA 11/2021 - 02/2011
7	Monoclonal AntibodiesIBA 08/2021 - 10/2006
7	Small Interfering RNA (siRNA)IBA 07/2021 - 12/2006
7	Cantharidin (Cantharides)IBA 02/2021 - 11/2011
7	Hormones (Hormone)IBA 01/2021 - 02/2015
6	Apolipoproteins E (ApoE)IBA 03/2022 - 12/2015
6	ErbB Receptors (EGF Receptor)IBA 01/2022 - 06/2007
6	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 07/2015
6	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 08/2008
6	AntigensIBA 01/2021 - 06/2008
6	CateninsIBA 01/2019 - 09/2013
6	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2016 - 11/2011
5	oxidized low density lipoproteinIBA 03/2022 - 07/2003
5	Arginine (L-Arginine)FDA Link 01/2022 - 08/2008
5	AntioxidantsIBA 01/2022 - 09/2008
5	Gemcitabine FDA Link 01/2022 - 07/2016

Therapy/Procedure

93	Therapeutics 03/2022 - 03/2002
35	Drug Therapy (Chemotherapy) 01/2022 - 02/2011
15	Radiotherapy 09/2020 - 11/2014
13	Segmental Mastectomy (Lumpectomy) 06/2021 - 12/2011
10	Neoadjuvant Therapy 01/2022 - 01/2011
9	Length of Stay 01/2022 - 04/2014
7	Mastectomy (Mammectomy) 05/2019 - 01/2015
6	Punctures 11/2022 - 03/2011
6	Precision Medicine 01/2022 - 01/2014
6	Transplantation 01/2022 - 04/2009
6	Ligation 10/2021 - 02/2008